In agreement with the last will of Doge Francesco Erizzo († 1646), his heart was buried in San Marco, the political and religious center of the Serenissima, next to the high altar and thus ad sanctos to the relics of Venice’s patron saint. This unprecedented privilege not only disrupted the city’s restrictive policies concerning public monuments, but her republican ideals in general. Due to the significance of the heart in Christian eschatological thinking and corporal state doctrines his burial elevated Erizzo to the status of an absolute ruler threatening the Republic’s sacred constitution. In Venice, however, individual and public interests were closely intertwined. This study therefore analyzes the heart burial in the context of Erizzo’s self-fashioning, Venetian state ideology, devotional practices, and collective memory.